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ea0098c16 | Clinical – Chemo/SSA/Biologics | NANETS2023

Comparison of well-differentiated gastroenteropancreatic grade 3 neuroendocrine tumors (G3NETS): de novo and in the setting of apparent grade progression over time

Khuong Le Bryan , Paciorek Alan , Moon Farhana , Lawhn Heath Courtney , Hope Thomas , Fidelman Nicholas , Mulvey Claire , Lindsay Sheila , Zhang¬ Li , Nakakura Eric , Joseph Nancy , Bergsland Emily K.

Background: G3NETs demonstrate variable clinical behavior (Ki-67>20-100%). Treatment extrapolated from grade 1/2 (G1/2) NETs and neuroendocrine carcinomas depending on clinicopathologic features. Therapy for treatment-emergent G3NETs remains especially ill-defined.Methods: Retrospective chart review of patients with de novo G3NETs or progressing from low-to-high grade (L-H) (G1/2 at diagnosis and G3 >=3 months later). Treatment patterns compared ...

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Endocrine Abstracts

Comparison of well-differentiated gastroenteropancreatic grade 3 neuroendocrine tumors (G3NETS): de novo and in the setting of apparent grade progression over time

BiosciAbstracts